A look a new findings todya on the genetic pathways that regulate the growth of ovarian cancers.
WASHINGTON (AP) — If breast cancer runs in the family, women can be at high risk even if they test free of the disease’s most common gene mutations, sobering new research shows. The genes BRCA1 and BRCA2 are linked with particularly a...
Information on Ovarian Cancer and the search for early detection that every woman should read.
Two new monotetrahydrofuran Annonaceous acetogenins, montacin (1), and cis-montacin (2), along with four known acetogenins, annonacin, cis-annonacin, annomontacin, and cis-annomontacin, were isolated from the seeds of Annona montana. The structures of the new isolates were elucidated by spectral and chemical methods. The new acetogenins exhibited moderate in vitro cytotoxic activity against the 1A9 human ovarian cancer cell line. Interestingly, when Ca2+ was present, compounds 1 and 2 become 3- to 10-fold more active against 1A9 cells and the PTX10 subline.
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Bullatacin, a compound isolated from plants of the Annonaceae, and its analogues show in vivo potential as antitumor agents based on their efficacy in normal mice bearing L1210 murine leukemia and athymic mice bearing A2780 conventional ovarian cancer xenografts. These compounds also have interesting potential as insecticides and inhibit respiration in insect-derived Sf9 cells with high potency. Their toxicity in both cases probably arises from their strong inhibition of mitochondrial electron transport with a specific action at complex I.
Researchers used ginger powder, similar to what is sold at grocery stores, only a standardized research grade. The ginger powder was dissolved in solution and applied to ovarian cancer cell cultures. Ginger induced cell death in all the ovarian cancer cell lines tested. Moreover, the researchers found that ginger caused two types of cell death. One type, known as apoptosis, results from cancer cells essentially committing suicide. The other type of cell death, called autophagy, results from cells digesting or attacking themselves
Barack Obama's grandmother, whose personality and bearing shaped much of the life of the Democratic presidential contender, has died, Obama announced Monday, one day before the election. Madelyn Payne Dunham was 86. News, Headlines and Latest Stories on Yahoo! News
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Around 1.5 percent of women are likely to develop ovarian cancer at some stage of their life. It is less common than breast cancer but is considered as the most serious and fatal of all gynecological cancers.